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Basics of NMR-based metabolomics

Event Details:

  • Date: - -
  • Venue: Collegio A. Volta, Pavia
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On December 12, 2019 Andrea Motta, Consiglio Nazionale delle Ricerche (CNR) Istituto di Chimica Biomolecolare (ICB), will given a presentation entitled Basics of NMR-based metabolomics at 16:00 in the College Lecture theatre at Colegio A. Volta. All students are invited to attend, especially those reading Medicine, Biology, Biotechnology and Pharmaceutical Sciences.

The poster of the lecture can be downloaded here.

Abstract
The NMR basics will be introduced and the technical application to metabolomics will be discussed. Examples will be taken from our studies on respiratory diseases. The NMR basics will be introduced and the technical application to metabolomics will be discussed. Examples will be taken from our studies on respiratory diseases.

Biography
1982 –1985. Post doc at the Dept of Chemistry, Carnegie-Mellon University, Pittsburgh PA, USA: NMR studies of human plasminogen (supervisor Prof. Miguel Llinás).
1995–up to now. Head of the NMR Service of Research Area “Naples 3”.
2002–up to now. “Dirigente di Ricerca”(Research Director) at Institute of Biomolecular Chemistry of CNR.
He has published over 170 papers, and served as referee for several Journals like PLoS Medicine, Biochemistry, Analytical Chemistry, Journal of Physical Chemistry, Journal of Proteome Research, Bioanalysis, European Respiratory Journal, Biomarkers in Medicine, Journal of Allergy and Clinical Immunology, etc.
He also served as project evaluator for the “National Science Foundation” (Washington DC, USA), the “International Science Foundation” (Washington DC, USA), the Human Frontier Science Program Organization (Strasbourg, France), and the EU.
Areas of Expertise
1. NMR structure determination ofpeptides and proteins involved in pathological processes: Structure-activity relationship of macromolecules; Design of new NMR experiments; Software development for NMR processing; Conformational calculations.
2. Metabolomics and metabonomics of pathologies: Metabolomics/metabonomics by high-resolution NMR; Statistical analysis.
3. Cell systems biology: Metabolic profiles of in-vivocells; Design of new NMR experiments for fast observation of metabolic fingerprint; Metabolic pathway bioinformatics
http://www.icb.cnr.it/en/index.php/personnel/researchers/87-motta-andrea

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The First DNA Fingerprint (Wellcome Collection)

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