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Resonance in Biology

Event Details:

  • Date: - -
  • Venue: (Seminar room, first floor) Collegio A Volta, Pavia
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Resonance in Biology

When: Pavia 13th-14th September 2019

Where: Volta College, Seminar room, first floor

Download the event poster here: resonance_poster_nero.pdf (23 downloads) .

The event is free but you are kindly requested to register in Eventbritehttps://www.eventbrite.co.uk/e/resonance-in-biology-tickets-65930579137

Why: We are holding a meeting in Pavia on the 13th and 14th of September to have ways to present applications of Biological nuclear magnetic resonance (NMR), a technique which will soon be represented in Pavia thanks to the arrival of the new 700 MHz Instrument.

Pavia is not new to this technique: Luigi Giulotto (1911-1986), a physics professor of University of Pavia, carried out seminal experiments to detect the NMR signal in liquid samples immediately after the discovery of NMR by Felix Bloch and Edward Mills Purcell in the immediate post-war period. Giulotto created around him a group of valid experimental physicists who obtained important results in nuclear and molecular spectroscopy. Giulotto’s work brought Pavia to a level of international visibility and established Pavia University as the first Italian research center in this sector.

The September meeting is meant to celebrate the 80th birthday of Pierandrea Temussi, the founder, together with Anna Laura Segre, of NMR in Italy. After getting his degree in Naples he entered very early on at the same University first as an assistant and later on as associated and then full professor. Temussi left to the States in 1965-66 where he worked in Urbana-Champain, Illinois, in the group of Prof. Gutowsky, the first to apply NMR methods to the field of chemistry. They published together Gutowsky, H. S. and Temussi, P. A. (1967) Conformational Isomerization of Hexahydro-1,3,5-Trimethyl-1,3,5-Triazine. J. Amer. Chem. Soc. 89, 4358. In 1967, Temussi spent a short period in Israel in Prof. Lifson’s group at the Weizman, just in time to see the end of the six days war. The first publications in NMR came around 1973 (Bradbury, E. M., Crane-Robinson, C., Paolillo, L. and Temussi, P. A. (1973) NMR Studies of a Polypeptide in a Non-protonating Solvent System. J. Amer. Chem. Soc. 95, 1638 and Bradbury, E. M., Crane-Robinson, C., Paolillo, L. and Temussi, P. A. (1973) NMR Studies of the Helix-Coil Transition of Polypeptides in Non-protonating Solvent Mixtures Polymer 14, 303). In 1976, he studied the structure of aspartame, immediately after the dipeptide was introduced as a sweetener. This was only the beginning of more than 30 years studies on biological active peptides. At the end of the ‘90ies, Temussi moved to study proteins, focusing mostly on the sweet protein monellin. Over the last 15 years, his main topic of interest is the study of crowding and confinements by NMR, a field in which he has published more than 20 articles

This event is under the auspices of the Initiative for Development and Engineering of Antibodies (IDEA) and was sponsored by the Frontiers journal and Bruker Italy.

Tentative program

Day 1 – 13th of September
14.00-14.15 Ermanno Gherardi (UniPv)
14.15-14.45 Attilio Rigamonti (UniPv)
14.45-15.30 Janez Plavec (Slovenian NMR Centre)

15.30-15.45 Coffee break

15.45-16.15 Rita Puglisi (King’s College London)
16.15-16.45 Giovanna Musco (UniMi)
16.45-17.15 Giorgio Colombo (UniPv)

Day 2 – 14th of September
9.30-10.15 Sasi Conte (King’s College London)
10.15-10.45 Chiara Marabelli (UniPv)

10.45-11.00 Coffee break

11.00-11.30 Caterina Alfano (RiMed)
11.30-12.00 Roberta Spadaccini (UniSannio)
12.00-12.30 Annamaria D’Ursi (UniSa)
12.30-13.00 Neri Niccolai (UniSi)

13.00-14.00 Lunch

14.00-14.45 Mario Piccioli (UniFi)
14.45-15.15 Orlando Crescenzi (UniNa)

15.15-15.30 Coffee break

15.30-16.00 Stefano Mammi (UniPd)
16.00-16.30 Mariagrazia Pizza (GSK)
16.30-17.00 Claudio Toniolo (UniPd)
17.00-17.10 Concluding Remarks

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